U.S. Pruritus Treatment Market

U.S. Pruritus Treatment Market (Pruritus Type: Systemic Diseases, Skin Diseases, Neurologic Diseases, Nocturnal Pruritus, Pruritus Ani, and Others) - Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2023-2031

U.S. Pruritus Treatment Market Outlook 2031

  • The market in the country was valued at US$ 5.1 Bn in 2022
  • It is projected to grow at a CAGR of 5.6% from 2023 to 2031 and reach more than US$ 8.4 Bn by 2031

Analysts’ Viewpoint

The pruritus treatment market in the U.S. is expected to witness significant growth in the next few years due to rise in prevalence of pruritus among the population. Surge in the geriatric population and increase in incidence of chronic diseases, such as diabetes and kidney diseases, are likely to propel market expansion. Furthermore, increase in awareness about the condition and availability of advanced treatment options, such as topical corticosteroids, antihistamines, and immunosuppressant, are projected to augment U.S. pruritus treatment industry growth in the next few years.

Rise in demand for over-the-counter (OTC) medications and surge in adoption of telemedicine are expected to offer lucrative opportunities to market players. Companies in the market are focusing on developing low cost and efficient OTC medications in order to increase market share and presence.

However, high cost of treatment and side effects associated with certain medications are likely to restrain the market.

Us Pruritus Treatment Market

U.S. Pruritus Treatment Market Introduction

Pruritus, commonly known as itching, is a common symptom of various skin conditions such as eczema, psoriasis, and dermatitis. It could also be a side effect of certain medications or a symptom of underlying medical conditions such as liver disease or kidney failure. Various types of pruritus treatment products are available in the market, including topical creams, ointments, lotions, oral medications, and phototherapy. Topical treatments are the most commonly used products for pruritus treatment, as these are easy to apply and provide quick relief. These itchy skin treatment products contain active ingredients such as corticosteroids, antihistamines, and local anesthetics that help to reduce inflammation and itching. However, prolonged use of topical treatments could cause skin thinning and other side effects.

Oral medications such as antihistamines and antidepressants are also used for pruritus treatment. These medications work by blocking the histamine receptors in the body and reducing the sensation of itching. However, these could cause drowsiness and other side effects. Phototherapy, which involves exposing the affected skin to ultraviolet light, is another treatment option for pruritus. It is a safe and effective treatment option; however, it requires specialized equipment and trained professionals to administer the treatment.

Rise in Prevalence of Skin Diseases

The prevalence of skin diseases has been increasing in the U.S. due to factors such as pollution, unhealthy lifestyle habits, and genetic predisposition. According to the American Academy of Dermatology Association (AADA), around 50 million people in the country suffer from acne each year. Moreover, the National Eczema Association states that over 31 million people in the U.S. have some form of eczema.

The rise in the prevalence of skin diseases has led to an increase in demand for pruritus treatment products in the country. Patients suffering from these conditions experience severe itching, which could lead to discomfort and affect the quality of life. Therefore, they seek effective treatments that can provide relief from itching symptoms. Furthermore, advancements in medical technology and research activities focused on developing new itching medicine for treating skin disorders such as pruritus are expected to propel the U.S. pruritus treatment market value.

A surge in Geriatric Population Propelling U.S. Pruritus Treatment Market Demand

The geriatric population is growing rapidly across the globe due to increased life expectancy rates and improved healthcare facilities leading to better health outcomes among older adults. According to data published by World Population Review, there were approximately 52 million people aged over 65 years old in the U.S. alone. Older adults are more prone to develop chronic illnesses including various types of skin disorders, such as atopic dermatitis or psoriasis. Hence, they experience pruritus symptoms more frequently than younger individuals.

Aging also causes changes in body physiology resulting in dryness or thinning out layers on the topmost layer i.e., the epidermis, making it more susceptible to itchiness caused by external stimuli such as clothing material. This is driving demand for anti-pruritic medications among elderly patients who require immediate relief from itching symptoms.

Increase in Awareness about Pruritic Skin Diseases

In terms of pruritus type, the skin diseases segment accounted for the largest U.S. pruritus treatment market share in 2022. This is ascribed to the high prevalence of skin diseases that cause pruritus among people in the country. According to a report published by the American Academy of Dermatology Association (AADA) in June 2021, around 85 million people in the country are affected by skin diseases every year. This includes conditions such as eczema and psoriasis, which are known to cause pruritus. Hence, the rise in demand for effective treatments for pruritic skin diseases has led to an increase in sales of anti-itch medication.

The surge in awareness about pruritic skin diseases among patients and healthcare professionals is another factor driving the skin diseases segment. Advancements in medical research and technology in the past few years have led to a greater understanding of how certain skin conditions can lead to chronic itching or pruritus. This has resulted in more accurate diagnosis and treatment options being made available, leading to an increase in demand for drugs targeting specific types of pruritus caused by different skin disorders.

High Effectiveness of Antihistamines against Various Allergies that Cause Itchiness

Based on drug type, the antihistamines segment dominated the U.S. pruritus treatment market in 2022. Antihistamines are effective against various types of allergy-causing itchiness, such as hives. These drugs work by blocking histamine receptors, thereby reducing inflammation associated with allergic reactions leading to relief from itching sensation. Moreover, antihistamines have fewer side effects compared to other drug classes used for treating itchiness, making it a preferred choice among patients. In May 2021, Pfizer, Inc. announced the launch of Xyzal Allergy 24HR, which is an antihistamine drug used for treating various types of allergies including pruritus caused by allergic reactions.

Ease of Administration and Better Patient Compliance Propelling Oral Segment

In terms of dosage form, the oral segment accounted for the largest market share in 2022. This is ascribed to ease of administration and better patient compliance compared with topical dosage forms. Oral medications are usually available in tablet or capsule form, making it easier for patients to take them as prescribed without having to worry about applying creams or ointments topically on affected areas. Furthermore, oral drugs have a longer duration of action compared to topical formulations, leading to sustained relief from itching sensation over a prolonged period. This has led to increase in demand for oral drugs targeting different types of pruritus caused by various underlying conditions.

Analysis of Key Players

The U.S. pruritus treatment market report includes vital information about the leading companies operating in the market. Leading players focus on strategies such as product launch, mergers & acquisitions (M&A), partnerships, and divestiture to increase market presence. AbbVie, Inc. (Allergan plc), Albireo Pharma, Inc., Astellas Pharma, Inc., Cipla Limited, Eli Lilly and Company, GSK plc, Merck & Co., Inc., Pfizer, Inc., Teva Pharmaceutical Industries Ltd., and Viatris, Inc. (Mylan N.V.) are the prominent players operating in the market.

Key Developments in U.S. Pruritus Treatment Market

  • In March 2023, Ipsen acquired Albireo Pharma, Inc. (a leading innovator in bile-acid modulators to treat pediatric and adult cholestatic liver diseases). The acquisition of Albireo will provide immediate incremental sales and strengthen Ipsen’s rare disease infrastructure. The acquisition is also anticipated to enrich Ipsen’s Rare Disease portfolio, with promising therapeutics for pediatric and adult rare cholestatic liver diseases, innovative pipeline potential, as well as scientific and commercial capabilities.
  • In March 2023, the U.S. Food and Drug Administration (FDA) accepted for review the supplemental Biologics License Application (sBLA) for Dupixent (dupilumab) to treat adults and adolescents aged 12 years and older with chronic spontaneous urticaria (CSU) that is not adequately controlled with the H1 antihistamine treatment, which is the current standard of care. The target action date for the FDA decision is October 22, 2023.
  • In July 2021, the U.S. Food & Drug Administration (FDA) approved Bylvay (odevixibat), the first drug approved for the itching treatment of pruritus in all subtypes of progressive familial intrahepatic cholestasis (PFIC). Bylvay is a potent, non-systemic ileal bile acid transport inhibitor (IBATi), which does not require refrigeration and is easily administered as a once-daily capsule or opened and sprinkled onto soft foods.

Each of these players has been profiled in the report based on parameters such as company overview, financial overview, business strategies, product portfolio, business segments, and recent developments.

U.S. Pruritus Treatment Market Snapshot

Attribute

Detail

Size in 2022

US$ 5.1 Bn

Forecast (Value) in 2031

More than US$ 8.4 Bn

Compound Annual Growth Rate (CAGR)

5.6%

Forecast Period

2023-2031

Historical Data Available for

2017-2021

Quantitative Units

US$ Bn for Value

Market Analysis

It includes segment analysis and qualitative analysis includes drivers, restraints, opportunities, key trends, and parent industry overview.

Competition Landscape

  • Market share analysis/ranking by company (2022)
  • Company profiles section includes overview, product portfolio, key subsidiaries or distributors, strategy & recent developments, and key financials

Format

Electronic (PDF) + Excel

Market Segmentation

  • Pruritus Type
    • Systemic Diseases
      • Cancer
      • Liver Disease
      • Kidney Disease
      • Others
    • Skin Diseases
      • Eczema
      • Atopic Dermatitis
      • Others
    • Neurologic Diseases
      • Shingles
      • Multiple Sclerosis
      • Others
    • Nocturnal Pruritus
    • Pruritus Ani
    • Others
  • Drug Type
    • Antihistamines
    • Calcineurin Inhibitors
    • Selective Serotonin Reuptake Inhibitors
    • Corticosteroids
    • Calamine
    • Neuroleptics
    • Others
  • Dosage Form
    • Topical
    • Oral
  • Sales Type
    • Rx Sales
    • OTC Sales
  • Distribution Channel
    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies

Companies Profiled

  • AbbVie, Inc. (Allergan plc)
  • Albireo Pharma, Inc.
  • Astellas Pharma Inc.
  • Cipla Limited
  • Eli Lilly and Company
  • GSK plc
  • Merck & Co., Inc.
  • Pfizer, Inc.
  • Teva Pharmaceutical Industries Ltd.
  • Viatris Inc. (Mylan N.V.)

Customization Scope

Available upon request

Pricing

Available upon request

Frequently Asked Questions

How big was the U.S. pruritus treatment market in 2022?

The industry was valued at US$ 5.1 Bn in 2022

How big will be the pruritus treatment market in the U.S. by 2031?

It is projected to reach more than US$ 8.4 Bn by 2031

What will be the CAGR of the U.S. pruritus treatment industry during the forecast period?

It is anticipated to grow at a CAGR of 5.6% from 2023 to 2031

Which are the prominent trends that affect U.S. pruritus treatment market growth?

Rise in prevalence of skin diseases and increase in geriatric population are driving the market in the country

Which was the leading market segment of the U.S. pruritus treatment?

The skin diseases segment accounted for the largest share of the industry in 2022

Who are the prominent players in the U.S. Pruritus Treatment Business?

AbbVie, Inc. (Allergan plc), Albireo Pharma, Inc., Astellas Pharma, Inc., Cipla Limited, Eli Lilly and Company, GSK plc, Merck & Co., Inc., Pfizer, Inc., Teva Pharmaceutical Industries Ltd., and Viatris, Inc. (Mylan N.V.)

    1. Preface

        1.2. Market Segmentation

        1.3. Key Research Objectives

        1.4. Research Highlights

    2. Assumptions and Research Methodology

    3. Executive Summary: U.S. Pruritus Treatment Market

    4. Market Overview

        4.1. Overview

        4.2. Market Dynamics

            4.2.1. Drivers

            4.2.2. Restraints

            4.2.3. Opportunities

        4.3. U.S. Pruritus Treatment Market Analysis and Forecast, 2017-2031

            4.3.1. Market Revenue Projections (US$ Mn)

            4.3.2. Market Volume Projections (Thousand Units)

    5. Key Insights

        5.1. Porter’s Five Forces Analysis

        5.2. Disease Prevalence & Incidence Rate

        5.3. Pricing Analysis

        5.4. Overview and Application of OTC Products in Treatment of Pruritus

        5.5. COVID-19 Impact Analysis

    6. U.S. Pruritus Treatment Market Analysis and Forecast, by Pruritus Type

        6.1. Introduction & Definition

        6.2. Key Findings/Developments

        6.3. Market Value Forecast, by Pruritus Type, 2017-2031

            6.3.1. Systemic Diseases

                6.3.1.1. Cancer

                6.3.1.2. Liver Disease

                6.3.1.3. Kidney Disease

                6.3.1.4. Others

            6.3.2. Skin Diseases

                6.3.2.1. Eczema

                6.3.2.2. Atopic Dermatitis

                6.3.2.3. Others

            6.3.3. Neurologic Diseases

                6.3.3.1. Shingles

                6.3.3.2. Multiple Sclerosis

                6.3.3.3. Others

            6.3.4. Nocturnal Pruritus

            6.3.5. Pruritus Ani

            6.3.6. Others

        6.4. Market Attractiveness Analysis, by Pruritus Type

    7. U.S. Pruritus Treatment Market Analysis and Forecast, by Drug Type

        7.1. Introduction & Definition

        7.2. Key Findings/Developments

        7.3. Market Value & Volume Forecast, by Drug Type, 2017-2031

            7.3.1. Antihistamines

            7.3.2. Calcineurin Inhibitors

            7.3.3. Selective Serotonin Reuptake Inhibitors

            7.3.4. Corticosteroids

            7.3.5. Calamine

            7.3.6. Neuroleptics

            7.3.7. Others

        7.4. Market Attractiveness Analysis, by Drug Type

    8. U.S. Pruritus Treatment Market Analysis and Forecast, by Sales Type

        8.1. Introduction & Definition

        8.2. Key Findings/Developments

        8.3. Market Value & Volume Forecast, by Sales Type, 2017 - 2031

            8.3.1. Rx Sales

            8.3.2. OTC Sales

        8.4. Market Attractiveness Analysis, by Sales Type

    9. U.S. Pruritus Treatment Market Analysis and Forecast, by Dosage Form

        9.1. Introduction & Definition

        9.2. Key Findings/Developments

        9.3. Market Value & Volume Forecast, by Dosage Form, 2017-2031

            9.3.1. Topical

            9.3.2. Oral

        9.4. Market Attractiveness Analysis, by Dosages Form

    10. U.S. Pruritus Treatment Market Analysis and Forecast, by Distribution Channel

        10.1. Introduction & Definition

        10.2. Key Findings/Developments

        10.3. Market Value Forecast, by Distribution Channel, 2017-2031

            10.3.1. Hospital Pharmacies

            10.3.2. Retail Pharmacies

            10.3.3. Online Pharmacies

        10.4. Market Attractiveness Analysis, by Distribution Channel

    11. Competition Landscape

        11.1. Market Player - Competition Matrix (by tier and size of companies)

        11.2. Market Share Analysis, by Company, 2021

        11.3. Company Profiles

            11.3.1. AbbVie, Inc. (Allergan plc)

                11.3.1.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.1.2. Test Type Portfolio

                11.3.1.3. Financial Overview

                11.3.1.4. SWOT Analysis

                11.3.1.5. Strategic Overview

            11.3.2. Albireo Pharma, Inc.

                11.3.2.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.2.2. Test Type Portfolio

                11.3.2.3. Financial Overview

                11.3.2.4. SWOT Analysis

                11.3.2.5. Strategic Overview

            11.3.3. Astellas Pharma, Inc.

                11.3.3.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.3.2. Test Type Portfolio

                11.3.3.3. Financial Overview

                11.3.3.4. SWOT Analysis

                11.3.3.5. Strategic Overview

            11.3.4. Cipla Limited

                11.3.4.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.4.2. Test Type Portfolio

                11.3.4.3. Financial Overview

                11.3.4.4. SWOT Analysis

                11.3.4.5. Strategic Overview

            11.3.5. Eli Lilly and Company

                11.3.5.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.5.2. Test Type Portfolio

                11.3.5.3. Financial Overview

                11.3.5.4. SWOT Analysis

                11.3.5.5. Strategic Overview

            11.3.6. GSK plc

                11.3.6.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.6.2. Test Type Portfolio

                11.3.6.3. Financial Overview

                11.3.6.4. SWOT Analysis

                11.3.6.5. Strategic Overview

            11.3.7. Merck & Co., Inc.

                11.3.7.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.7.2. Test Type Portfolio

                11.3.7.3. Financial Overview

                11.3.7.4. SWOT Analysis

                11.3.7.5. Strategic Overview

            11.3.8. Pfizer, Inc.

                11.3.8.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.8.2. Test Type Portfolio

                11.3.8.3. Financial Overview

                11.3.8.4. SWOT Analysis

                11.3.8.5. Strategic Overview

            11.3.9. Teva Pharmaceutical Industries Ltd.

                11.3.9.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.9.2. Test Type Portfolio

                11.3.9.3. Financial Overview

                11.3.9.4. SWOT Analysis

                11.3.9.5. Strategic Overview

            11.3.10. Viatris Inc. (Mylan N.V.)

                11.3.10.1. Company Overview (HQ, Business Segments, Employee Strength)

                11.3.10.2. Test Type Portfolio

                11.3.10.3. Financial Overview

                11.3.10.4. SWOT Analysis

                11.3.10.5. Strategic Overview

    List of Tables

    Table 01: U.S. Pruritus Treatment Market Value (US$ Mn) Forecast, by Pruritus Type, 2017-2031

    Table 02: U.S. Pruritus Treatment Market Value (US$ Mn) Forecast, by Systemic Diseases, 2017-2031

    Table 03: U.S. Pruritus Treatment Market Value (US$ Mn) Forecast, by Skin Diseases, 2017-2031

    Table 04: U.S. Pruritus Treatment Market Value (US$ Mn) Forecast, by Neurologic Diseases, 2017-2031

    Table 05: U.S. Pruritus Treatment Market Value (US$ Mn) Forecast, by Drug Type, 2017-2031

    Table 06: U.S. Pruritus Treatment Market Volume (Thousand Units) Forecast, by Drug Type, 2017-2031

    Table 07: U.S. Pruritus Treatment Market Value (US$ Mn) Forecast, by Sales Type, 2017-2031

    Table 08: U.S. Pruritus Treatment Market Volume (Thousand Units) Forecast, by Sales Type, 2017-2031

    Table 09: U.S. Pruritus Treatment Market Value (US$ Mn) Forecast, by Dosage Form, 2017-2031

    Table 10: U.S. Pruritus Treatment Market Volume (Thousand Units) Forecast, by Dosage Form, 2017-2031

    Table 11: U.S. Pruritus Treatment Market Value (US$ Mn) Forecast, by Distribution Channel, 2017-2031

    List of Figures

    Figure 01: U.S. Pruritus Treatment Market Value (US$ Mn) Forecast, 2017-2031

    Figure 02: U.S. Pruritus Treatment Market Volume (Thousand Units) Forecast, 2017-2031

    Figure 03: U.S. Pruritus Treatment Market Value Share, by Pruritus Type, 2022

    Figure 04: U.S. Pruritus Treatment Market Value Share, by Drug Type, 2022

    Figure 05: U.S. Pruritus Treatment Market Value Share, by Sales Type, 2022

    Figure 06: U.S. Pruritus Treatment Market Value Share, by Dosage Form, 2022

    Figure 07: U.S. Pruritus Treatment Market Value Share, by Distribution Channel, 2022

    Figure 08: U.S. Pruritus Treatment Market Value Share Analysis, by Pruritus Type, 2022 and 2031

    Figure 09: U.S. Pruritus Treatment Market Attractiveness Analysis, by Pruritus Type, 2023-2031

    Figure 10: U.S. Pruritus Treatment Market (US$ Mn), by Systemic Diseases, 2017-2031

    Figure 11: U.S. Pruritus Treatment Market (US$ Mn), by Skin Diseases, 2017-2031

    Figure 12: U.S. Pruritus Treatment Market (US$ Mn), by Neurologic Diseases, 2017-2031

    Figure 13: U.S. Pruritus Treatment Market (US$ Mn), by Nocturnal Pruritus, 2017-2031

    Figure 14: U.S. Pruritus Treatment Market (US$ Mn), by Pruritus Ani, 2017-2031

    Figure 15: U.S. Pruritus Treatment Market (US$ Mn), by Nocturnal Pruritus, 2017-2031

    Figure 16: U.S. Pruritus Treatment Market Value Share Analysis, by Drug Type, 2022 and 2031

    Figure 17: U.S. Pruritus Treatment Market Attractiveness Analysis, by Drug Type, 2023-2031

    Figure 18: U.S. Pruritus Treatment Market (US$ Mn), by Antihistamines, 2017-2031

    Figure 19: U.S. Pruritus Treatment Market (US$ Mn), by Calcineurin Inhibitors, 2017-2031

    Figure 20: U.S. Pruritus Treatment Market (US$ Mn), by Selective Serotonin Reuptake Inhibitors, 2017-2031

    Figure 21: U.S. Pruritus Treatment Market (US$ Mn), by Corticosteroids, 2017-2031

    Figure 22: U.S. Pruritus Treatment Market (US$ Mn), by Calamine, 2017-2031

    Figure 23: U.S. Pruritus Treatment Market (US$ Mn), by Corticosteroids, 2017-2031

    Figure 24: U.S. Pruritus Treatment Market (US$ Mn), by Others, 2017-2031

    Figure 25: U.S. Pruritus Treatment Market Value Share Analysis, by Sales Type, 2022 and 2031

    Figure 26: U.S. Pruritus Treatment Market Attractiveness Analysis, by Sales Type, 2023-2031

    Figure 27: U.S. Pruritus Treatment Market (US$ Mn), by Rx Sales, 2017-2031

    Figure 28: U.S. Pruritus Treatment Market (US$ Mn), by OTC Sales, 2017-2031

    Figure 29: U.S. Pruritus Treatment Market Value Share Analysis, by Dosage Form, 2022 and 2031

    Figure 30: U.S. Pruritus Treatment Market Attractiveness Analysis, by Dosage Form, 2023-2031

    Figure 31: U.S. Pruritus Treatment Market (US$ Mn), by Topical, 2017-2031

    Figure 32: U.S. Pruritus Treatment Market (US$ Mn), by Oral, 2017-2031

    Figure 33: U.S. Pruritus Treatment Market Value Share Analysis, by Distribution Channel, 2022 and 2031

    Figure 34: U.S. Pruritus Treatment Market Attractiveness Analysis, by Distribution Channel, 2023-2031

    Figure 35: U.S. Pruritus Treatment Market (US$ Mn), by Hospital Pharmacies, 2017-2031

    Figure 36: U.S. Pruritus Treatment Market (US$ Mn), by Retail Pharmacies, 2017-2031

    Figure 37: U.S. Pruritus Treatment Market (US$ Mn), by Online Pharmacies, 2017-2031

    Figure 38: U.S. Pruritus Treatment Market Share Analysis, by Company, 2022

Copyright © Transparency Market Research, Inc. All Rights reserved