Novel Drug Delivery Systems (NDDS) in Cancer Therapy Market

Novel Drug Delivery Systems (NDDS) in Cancer Therapy Market (Drug Eluting Beads, Polyvinyl Alcohol (PVA) Particles, Microspheres, Gelatin-based Embolization Devices, Selective Internal Radiation Therapy (SIRT), Onyx, TRUFILL n Butyl Cyano Acrylate (nBCA) Liquid Embolic System and Nanoparticles) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020

Novel Drug Delivery Systems (NDDS) in Cancer Therapy Market - Snapshot

Novel drug delivery systems come with several points of interest, which include better therapies by increasing the duration and efficacy of drug activity. It has also offers better patient compliance via diminished frequency of dose. It also offers suitable routes of drug administration and improved targeting for a specific site to expect hurtful reactions. The various types of high-end drug delivery approach is such as microcapsules, liposomes, nanoemulsion, nano capsules, hydrogels, microsphere, nanoparticles, and polymeric are expressed using plant and bioactive extracts.

The global novel drug delivery systems market is likely to witness expansion due to substantial benefits over traditional therapies for treatment of cancer. Such treatments of cancer come with bioavailability and solubility, low toxicity, sustained and controlled drug delivery, improvement in stability, protection against biochemical and physical degradation and optimum therapeutic effect.

Rise in Prevalence of Cancer Likely to Shoot Up Demand in Near Future

The global novel drug delivery systems market is mainly influenced by a rise in the incidences of cancer. In addition, rise in research activities for the development of technologies of novel drug delivery coupled with augmented funding for ongoing research projects.

In addition, there has been a rise in healthcare expenditure for the treatment and diagnosis of cancer, which is likely to further add to the growth of the global novel drug delivery systems market. A rise in awareness about various alternative therapies is likely to support developments in the global novel drug delivery systems market in the years to come.

North America is estimated to account for a leading share of the global novel drug delivery systems market over the tenure of assessment. In addition, presence of several manufacturers together with availability of research funding for introduction of new methods of treatment is anticipated to support growth of the market in North America. Furthermore, there are many ongoing regulatory approvals in process for the introduction of new drugs in the North America novel drug delivery systems market.

The world is witnessing a continuous rise in the incidence of various types of cancer. Clinical benefits of embolic agents and nanoparticles over other therapy and drug delivery systems; technological advances leading to the development of new and innovative therapy; and expanding therapeutic indications of existing NDDS are some of the major factors expected to drive growth of the global NDDS in cancer therapy market during the forecast period from 2014 to 2020. On the other hand, factors such as high treatment cost associated with NDDS, strict regulatory pathways and cost associated with new product development may restrict market growth to some extent. One of the major opportunities in this market is nano-enabled drug delivery systems as this segment has been anticipated to grow at the highest CAGR of 24.7% during the forecast period.

The global market for NDDS in cancer therapy was valued at USD 3,655.3 million in 2013 and is expected to reach USD 15,984.2 million in 2020, growing at a CAGR of 23.7% during the forecast period from 2014 to 2020. Embolization particles, liquid embolics and nanoparticles as drug delivery systems altogether comprise the global market for NDDS in cancer therapy. PVA particles, microspheres, drug eluting beads (DEB) and selective internal radiation therapy (SIRT) are the major products under the embolization particles market segment, while Onyx LES and TRUFILL nBCA LES are the two major liquid embolic system brands. The liquid embolics market segment is expected to grow at a CAGR of 4.9% during the forecast period from 2014 to 2020. Nanoparticles in novel drug delivery systems have emerged as a promising technology to treat patients suffering from various types of cancer. The market for nanoparticles segment was valued at USD 3,307.7 million in 2013 with the largest revenue share in the overall NDDS in cancer therapy market. Over the past two decades, many nanoparticles such as Doxil (doxorubicin), Megace ES (megestrol acetate), Abraxane (paclitaxel), Myocet (doxorubicin), DepoCyt (liposomal cytarabine), and DaunoXome (daunorubicin citrate) have been approved as drug delivery systems for cancer therapy. 

Geographically, North America was the largest regional market for NDDS in cancer therapy in 2013, with a market share of 46.6%. Growing at a CAGR of 24.9% during the forecast period 2014 to 2020, its market share is expected to reach 49.7% in 2020. Europe captured the second largest share after North America and accounted for 29.2% of the global market revenue in 2013. In the Asia Pacific region, Japan, China, India, Australia and New Zealand are the potential markets that offer enormous opportunities for NDDS in cancer therapy market to grow substantially in the region. Major factors that will be responsible for market growth in these markets include emerging economies, growing market penetration by major players in these regions and improvement in reimbursement scenario. The Asia Pacific market is expected to grow at a CAGR of 22.6% during the forecast period.

The key players operating in the NDDS in cancer therapy market are Advanced Medical Isotope Corporation, Bind Therapeutics, Boston Scientific Corporation, BTG plc, CeloNova BioSciences, Inc., Cook Medical, Inc., Cospheric LLC, Covidien, plc, Eckert & Ziegler BEBIG, EmboMedics, Inc., Kobo Products, Inc., Merit Medical Systems, Inc., Mo-Sci Corporation, Nanobiotix, Polysciences, Inc., Sirtex Medical, Inc. and Terumo Medical Corporation.

     
    Chapter 1 Preface
    1.1 Report Description
    1.2 Market Segmentation
    1.3 Research Methodology
         1.3.1 Sources
                 1.3.1.1 Secondary Research
                 1.3.1.2 Primary Research
         1.3.2 Assumptions and Limitations
         1.3.3 List of Abbreviations
     
    Chapter 2 Executive Summary
    2.1 Market Snapshot: Global NDDS in Cancer Therapy Market (2013 & 2020)
    2.2 Global NDDS in Cancer Therapy Market, by Technology, 2013 (USD Million)
    2.3 Comparative Analysis: Global NDDS in Cancer Therapy Market Revenue, by Geography, 2013 & 2020 (Value %)
     
    Chapter 3 Market Overview
    3.1 Introduction
    3.2 Global Prevalence and Incidence Data
         3.2.1 Global Historical Prevalence (Number of Cases), by Major Cancer Type (2008 - 2012)
         3.2.2 Global Prevalence Forecast (Number of Cases), by Major Cancer Type (2013 - 2020)
         3.2.3 Global Historical Incidence (Number of Cases), by Major Cancer Type (2008 - 2012)
         3.2.4 Global Incidence Forecast (Number of Cases), by Major Cancer Type (2013 - 2020)
    3.3 Current Major Indications for NDDS in Cancer Therapy
         3.3.1 Liver Cancer
         3.3.2 Pancreatic Cancer
         3.3.3 Bile Duct Cancer
         3.3.4 Colorectal Cancer
         3.3.5 Arteriovenous Malformations
         3.3.6 Hypervascular Malignant Tumors
         3.3.7 Aneurysms
    3.4 Drivers
         3.4.1 Growing incidence of various types of cancer
         3.4.2 Clinical benefits of embolic agents and nanoparticles over other therapy and drug delivery systems
         3.4.3 Technological advances leading to the development of new and innovative therapy
         3.4.4 Expanding therapeutic indications of NDDS
    3.5 Restraints
         3.5.1 High treatment cost associated with NDDS
         3.5.2 Strict regulatory pathway and high cost associated with new product development
    3.6 Opportunities
         3.6.1 Investing in the development of nano-enabled drug delivery systems
    3.7 Regulatory Pathway to Commercialization
         3.7.1 U.S. Food and Drug Administration (FDA)
                 3.7.1.1 Major Steps: U.S. FDA Regulatory Approval Pathway
         3.7.2 EU (CE Marking)
                 3.7.2.1 Major Steps: CE Marking Regulatory Approval Pathway
    3.8 Event Impact Analysis
    3.9 Market Attractiveness Analysis: Global NDDS in Cancer Therapy Market, by Geography
     
    Chapter 4 Global Embolization Particles Market Revenue, by Type
    4.1 Overview
         4.1.1 Global Embolization Particles Market Revenue, by Type, 2012 - 2020 (USD Million)
    4.2 Current Technologies
         4.2.1 Drug Eluting Beads
                 4.2.1.1 Global Drug Eluting Beads Market Revenue, 2012 - 2020 (USD Million)
         4.2.2 Other Current Technologies
                 4.2.2.1 Global Other Current Technologies Market Revenue, 2012 - 2020 (USD Million)
                 4.2.2.2 Polyvinyl Alcohol (PVA) Particles
                 4.2.2.3 Microspheres
                 4.2.2.4 Gelatin-based Embolization Devices
    4.3 Emerging Technologies
         4.3.1 Selective Internal Radiation Therapy (SIRT) / Radioembolization
                 4.3.1.1 Global SIRT/ Radioembolization Market Revenue, 2012 - 2020 (USD Million)
                 4.3.1.2 SIR-Spheres Microspheres
                           4.3.1.2.1 Global SIR-Spheres Market Revenue, 2012 – 2020 (USD Million)
                 4.3.1.3 TheraSphere
                           4.3.1.3.1 Global TheraSphere Market Revenue, 2012 – 2020 (USD Million)
         4.3.2 Holmium-based Microspheres
    4.4 Recent Events
    4.5 Competitive Analysis
         4.5.1 Market Share Analysis: Embolization Particles, by Key Players, 2013 (Value %)
     
    Chapter 5 Global Liquid Embolics Market Revenue, by Brand
    5.1 Overview
         5.1.1 Global Liquid Embolics Market Revenue, by Brand, 2012 - 2020 (USD Million)
         5.1.2 Onyx
                 5.1.2.1 Global Onyx Devices Market Revenue, 2012 - 2020 (USD Million)
         5.1.3 TRUFILL n Butyl Cyano Acrylate (nBCA) Liquid Embolic System
                 5.1.3.1 Global TRUFILL nBCA Liquid Embolic Systems Market Revenue, 2012 – 2020 (USD Million)
    5.2 Recent Developments
    5.3 Competitive Analysis
         5.3.1 Market Share Analysis: Liquid Embolics, by Key Players, 2013 (Value %)
     
    Chapter 6 Global Nanoparticles Market Revenue
    6.1 Overview
         6.1.1 Global Nano-enabled Drug Delivery Systems in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)
         6.1.2 Approved Nano-enabled Drug Delivery Systems for Cancer Treatment
         6.1.3 Nano-enabled Drug Delivery Systems in Cancer Treatment Under Clinical Investigation
         6.1.4 Emerging Technologies and Treatments
                 6.1.4.1 Nanocarriers
    6.2 Competitive Analysis
         6.2.1 Market Share Analysis: Nanoparticles, by Key Players, 2013 (Value %)
     
    Chapter 7 Global NDDS in Cancer Therapy Market, by Geography
    7.1 Overview
         7.1.1 Global NDDS in Cancer Therapy Market Revenue, by Geography, 2012 - 2020 (USD Million)
    7.2 North America
         7.2.1 North America NDDS in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)
         7.2.2 North America NDDS in Cancer Therapy Market Revenue, by Technology, 2012 - 2020 (USD Million)
    7.3 Europe
         7.3.1 Europe NDDS in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)
         7.3.2 Europe NDDS in Cancer Therapy Market Revenue, by Technology, 2012 - 2020 (USD Million)
    7.4 Asia Pacific
         7.4.1 Asia Pacific NDDS in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)
         7.4.2 Asia Pacific NDDS in Cancer Therapy Market Revenue, by Technology, 2012 - 2020 (USD Million)
    7.5 Rest of the World
         7.5.1 Rest of the World NDDS in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)
         7.5.2 Rest of the World NDDS in Cancer Therapy Market Revenue, by Technology, 2012 - 2020 (USD Million)
     
    Chapter 8 Recommendations
    8.1 Strategies for Success
    8.2 ANSOFF Matrix
    List of Tables
     
    TABLE 1 List of Abbreviations
    TABLE 2 Market Snapshot: Global NDDS in Cancer Therapy Market (2013 & 2020)
    TABLE 3 Event Impact Analysis: Global NDDS in Cancer Therapy Market
    TABLE 4 Global Embolization Particles Market Revenue, by Type, 2012 - 2020 (USD Million)
    TABLE 5 Global Liquid Embolics Market Revenue (Forecast), by Brand, 2012 - 2020 (USD Million)
    TABLE 6 Approved Nano-enabled Drug Delivery Systems for Cancer Treatment
    TABLE 7 Nano-enabled Drug Delivery Systems in Cancer Treatment Under Clinical Investigation
    TABLE 8 Global NDDS in Cancer Therapy Market Revenue, by Geography, 2012 - 2020 (USD Million)
    TABLE 9 North America NDDS in Cancer Therapy Market Revenue, by Technology, 2012 – 2020 (USD Million)
    TABLE 10 Europe NDDS in Cancer Therapy Market Revenue, by Technology, 2012 - 2020 (USD Million)
    TABLE 11 Asia Pacific NDDS in Cancer Therapy Market Revenue, by Technology, 2012 - 2020 (USD Million)
    TABLE 12 Rest of the World NDDS in Cancer Therapy Market Revenue, by Technology, 2012 - 2020 (USD Million)

    List of Figures

     

    FIG. 1 Market Segmentation: NDDS in Cancer Therapy

    FIG. 2 Global NDDS in Cancer Therapy Market, by Technology, 2013 (USD Million)

    FIG. 3 Comparative Analysis: Global NDDS in Cancer Therapy Market Revenue, by Geography, 2013 & 2020 (Value %)

    FIG. 4 Global Historical Prevalence (Number of Cases), by Major Cancer Type (2008 - 2012)

    FIG. 5 Global Prevalence Forecast (Number of Cases), by Major Cancer Type (2013 - 2020)

    FIG. 6 Global Historical Incidence (Number of Cases), by Major Cancer Type (2008 - 2012)

    FIG. 7 Global Incidence Forecast (Number of Cases), by Major Cancer Type (2013 - 2020)

    FIG. 8 Major Steps: U.S. FDA Regulatory Approval Pathway

    FIG. 9 Major Steps: CE Marking Regulatory Approval Pathway

    FIG. 10 Market Attractiveness Analysis: Global NDDS in Cancer Therapy Market, by Geography

    FIG. 11 Global Drug Eluting Beads Market Revenue, 2012 – 2020 (USD Million)

    FIG. 12 Global Other Current Technologies Market Revenue, 2012 - 2020 (USD Million)

    FIG. 13 Global SIRT/ Radioembolization Market Revenue, 2012 - 2020 (USD Million)

    FIG. 14 Global SIR-Spheres Market Revenue, 2012 – 2020 (USD Million)

    FIG. 15 Global TheraSphere Market Revenue, 2012 – 2020 (USD Million)

    FIG. 16 Market Share Analysis: Embolization Particles, by Key Players, 2013 (Value %)

    FIG. 17 Global Onyx Devices Market Revenue, 2012 - 2020 (USD Million)

    FIG. 18 Global TRUFILL nBCA Liquid Embolic Systems Market Revenue, 2012 – 2020 (USD Million)

    FIG. 19 Market Share Analysis: Liquid Embolics, by Key Players, 2013 (Value %)

    FIG. 20 Global Nano-enabled Drug Delivery Systems in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)

    FIG. 21 Market Share Analysis: Nanoparticles, by Key Players, 2013 (Value %)

    FIG. 22 North America NDDS in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)

    FIG. 23 Europe NDDS in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)

    FIG. 24 Asia Pacific NDDS in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)

    FIG. 25 Rest of the World NDDS in Cancer Therapy Market Revenue, 2012 - 2020 (USD Million)

    FIG. 26 ANSOFF Matrix: NDDS in Cancer Therapy Market

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