Rise in the incidence of chronic diseases is the factor basically augmenting the natural APIs market. Active pharmaceutical ingredients (APIs) play a crucial role in human therapeutics, as they account for close to 20% of secondary metabolites.
Higher efficiency associated with genomics is helping the researchers in taking quick decisions regarding the usage of particular APIs. Natural APIs are devoid of side-effects, and therefore preferred in the modern parlance.
The natural APIs market manufacturers are working toward studying the outcome of extensively targeted metabolomics analysis, which reveals identifying major metabolites and antioxidants. They are also exploring the probabilities of reaching out to the untapped geographies of Middle East & Africa and Latin America.
The last few years have been witnessing exploration, extraction, and screening of herbs, spices, and several natural resources.
The phytochemicals, meaning the naturally occurring bioactive molecules generated from several plant sections are basically responsible for biological activities and widely adopted in pharmaceutical industry for developing numerous medications for treatment of several diseases.
Saponins, alkaloids, flavonoids, phenols, carbohydrates, steroids, and tannins are amongst the vital chemical compounds. The present scenario is such that more than 100 active agents are found to be obtained from plants and used in the production of drugs and medicines.
However, uncertainty revolving around the regulatory framework linked with plant-based APIs is expected to hamper the growth of the natural APIs market during the forecast period.
Attribute | Detail |
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Market Drivers |
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Active pharmaceutical ingredients (APIs) are referred to as biologically active components of the medications producing therapeutic effect. They are important in order to treat several health conditions, right from infectious to chronic illnesses and also mental health disorders.
Natural APIs are capable of imitating distinctive metabolites of the biological functionality such as naturally occurring ligands and hormones. They are also good at processing structural diversity, which is essential for the process of drug discovery.
As per the WHO, noncommunicable diseases (NCDs) end up killing 41 million people every year, which is equivalent to 74% of fatalities worldwide. Synthetic APIs are reported to produce side-effects such as nausea, back pain, stomach ache, etc.
Need to combat the side-effects caused by synthetic APIs while treating chronic diseases is thus accelerating the natural APIs market.
Breakthroughs in biotechnology are vital in healthcare as they help in revolutionizing treatments and enhance patient outcomes.
Advancements in biotechnology have made genome sequencing more affordable and accessible. In September 2022, Illumina launched NovaSeq X and NovaSeq X Plus, through which it claimed to reduce cost of sequencing an entire human genome to US$ 200.
NoveSeq X Plus has been reported to sequence 20,000 genomes every year, which is a noticeable improvement over previous machines that were capable of processing merely 7,500 genomes on a yearly basis and generate close to 16 TB of data in one run.
Arrangements of nucleotides in DNA determines sequence of the amino acids in proteins, which would, in turn, help in determining function of protein. It helps in basic biological research, in various applied fields such as biotechnology, medical diagnosis, virology, forensic biology, and biological systematics.
Generation of multiple genomes at a time thus helps in expediting the decision-making regarding usage of natural active pharmaceutical ingredients (APIs) in formulating drugs. This factor is catalyzing the natural APIs market, as researchers lose less time in deciding upon their usage.
Attribute | Detail |
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Leading Region | North America |
As per the latest natural APIs market analysis, North America led the natural APIs landscape in 2023 and the status quo is expected to remain unchanged during the forecast period. This is attributed to growing awareness amongst the population of the U.S. regarding benefits of intake of nutraceuticals to prevent/cure chronic diseases.
For instance, in June 2022, Antheia received funds worth US$ 40 Mn from Silicon Valley Bank and Oxford Finance LLC to develop biomanufacturing facility for the plant-based compounds.
Asia Pacific’s significant natural APIs market share is ascribed to initiatives being taken by private and public organizations for boosting production of natural API in this region.
For instance, in March 2022, the WHO announced that it had planned to construct the Global Centre for Traditional Medicine in India with the objective of maximizing conventional medicine’s potential using science and modern technology.
The key participants in the natural APIs market are launching new products to sustain amidst plant-based APIs landscape. For instance, in December 2023, Samabrivas platform amalgamated benefits of conventional production of APIs with plant-based ones in bioreactors for facilitating reliable, continuous, and environmentally-friendly production for the entire year.
Roquette Frères SA, Evonik Industries AG, Cargill, Inc., Novartis AG, Sanofi S.A., Kothari Phytochemicals & Industries Ltd., Centroflora Group, Arboris, LLC, BASF SE, and GSK plc are some of the key players covered in the natural APIs market report.
These companies have been profiled based on parameters such as company overview, business strategies, financial overview, product portfolio, and business segments.
Attribute | Detail |
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Market Size in 2023 | US$ 30.0 Bn |
Market Forecast (Value) in 2034 | US$ 57.5 Bn |
Growth Rate (CAGR) | 6.1% |
Forecast Period | 2024-2034 |
Historical Data Available for | 2020-2022 |
Quantitative Units | US$ Bn for Value |
Market Analysis | It includes segment analysis as well as regional level analysis. Moreover, qualitative analysis includes drivers, restraints, opportunities, key trends, Porter’s Five Forces analysis, value chain analysis, and key trend analysis. |
Competition Landscape |
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Format | Electronic (PDF) + Excel |
Market Segmentation |
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Regions Covered |
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Countries Covered |
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Companies Profiled |
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Customization Scope | Available Upon Request |
Pricing | Available Upon Request |
It was valued at US$ 30.0 Bn in 2023
It is projected to grow at a CAGR of 6.1% from 2024 to 2034
Growing prevalence of chronic disorders and rise in advancements in biotechnology and genomics
Biopharmaceutical companies segment accounted for the largest share in 2023
North America was the dominant region in 2023
Roquette Frères SA, Evonik Industries AG, Cargill, Inc., Novartis AG, Sanofi S.A., Kothari Phytochemicals & Industries Ltd., Centroflora Group, Arboris, LLC, BASF SE, and GSK plc
1. Preface
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary: Global Natural APIs Market
4. Market Overview
4.1. Introduction
4.1.1. Product Definition
4.1.2. Industry Evolution/Developments
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Natural APIs Market Analysis and Forecast, 2020-2034
5. Key Insights
5.1. Pipeline Analysis
5.2. Key Product/Brand Analysis
5.3. Key Mergers & Acquisitions
5.4. COVID-19 Pandemic Impact on Industry
6. Global Natural APIs Market Analysis and Forecast, by Molecule Type
6.1. Introduction & Definition
6.2. Key Findings/Developments
6.3. Market Value Forecast, by Molecule Type, 2020-2034
6.3.1. Alkaloids
6.3.2. Phenolic Acids
6.3.3. Terpenoids
6.3.4. Lignin & Stilbenes
6.3.5. Anthocyanin
6.3.6. Flavonoids
6.3.7. Others
6.4. Market Attractiveness Analysis, by Molecule Type
7. Global Natural APIs Market Analysis and Forecast, by End-user
7.1. Introduction & Definition
7.2. Key Findings/Developments
7.3. Market Value Forecast, by End-user, 2020-2034
7.3.1. Biopharmaceutical Companies
7.3.2. Nutraceutical Companies
7.3.3. Herbal-based Industries
7.3.4. Others (Research Institutes, etc.)
7.4. Market Attractiveness Analysis, by End-user
8. Global Natural APIs Market Analysis and Forecast, by Region
8.1. Key Findings
8.2. Market Value Forecast, by Region, 2020-2034
8.2.1. North America
8.2.2. Europe
8.2.3. Asia Pacific
8.2.4. Latin America
8.2.5. Middle East & Africa
8.3. Market Attractiveness Analysis, by Region
9. North America Natural APIs Market Analysis and Forecast
9.1. Introduction
9.2. Key Findings
9.3. Market Value Forecast, by Molecule Type, 2020-2034
9.3.1. Alkaloids
9.3.2. Phenolic Acids
9.3.3. Terpenoids
9.3.4. Lignin & Stilbenes
9.3.5. Anthocyanin
9.3.6. Flavonoids
9.3.7. Others
9.4. Market Value Forecast, by End-user, 2020-2034
9.4.1. Biopharmaceutical Companies
9.4.2. Nutraceutical Companies
9.4.3. Herbal-based Industries
9.4.4. Others (Research Institutes, etc.)
9.5. Market Value Forecast, by Country, 2020-2034
9.5.1. U.S.
9.5.2. Canada
9.6. Market Attractiveness Analysis
9.6.1. By Molecule Type
9.6.2. By End-user
9.6.3. By Country
10. Europe Natural APIs Market Analysis and Forecast
10.1. Introduction
10.2. Key Findings
10.3. Market Value Forecast, by Molecule Type, 2020-2034
10.3.1. Alkaloids
10.3.2. Phenolic Acids
10.3.3. Terpenoids
10.3.4. Lignin & Stilbenes
10.3.5. Anthocyanin
10.3.6. Flavonoids
10.3.7. Others
10.4. Market Value Forecast, by End-user, 2020-2034
10.4.1. Biopharmaceutical Companies
10.4.2. Nutraceutical Companies
10.4.3. Herbal-based Industries
10.4.4. Others (Research Institutes, etc.)
10.5. Market Value Forecast, by Country/Sub-region, 2020-2034
10.5.1. Germany
10.5.2. U.K.
10.5.3. France
10.5.4. Italy
10.5.5. Spain
10.5.6. Rest of Europe
10.6. Market Attractiveness Analysis
10.6.1. By Molecule Type
10.6.2. By End-user
10.6.3. By Country/Sub-region
11. Asia Pacific Natural APIs Market Analysis and Forecast
11.1. Introduction
11.2. Key Findings
11.3. Market Value Forecast, by Molecule Type, 2020-2034
11.3.1. Alkaloids
11.3.2. Phenolic Acids
11.3.3. Terpenoids
11.3.4. Lignin & Stilbenes
11.3.5. Anthocyanin
11.3.6. Flavonoids
11.3.7. Others
11.4. Market Value Forecast, by End-user, 2020-2034
11.4.1. Biopharmaceutical Companies
11.4.2. Nutraceutical Companies
11.4.3. Herbal-based Industries
11.4.4. Others (Research Institutes, etc.)
11.5. Market Value Forecast, by Country/Sub-region, 2020-2034
11.5.1. China
11.5.2. Japan
11.5.3. India
11.5.4. Australia & New Zealand
11.5.5. Rest of Asia Pacific
11.6. Market Attractiveness Analysis
11.6.1. By Molecule Type
11.6.2. By End-user
11.6.3. By Country/Sub-region
12. Latin America Natural APIs Market Analysis and Forecast
12.1. Introduction
12.2. Key Findings
12.3. Market Value Forecast, by Molecule Type, 2020-2034
12.3.1. Alkaloids
12.3.2. Phenolic Acids
12.3.3. Terpenoids
12.3.4. Lignin & Stilbenes
12.3.5. Anthocyanin
12.3.6. Flavonoids
12.3.7. Others
12.4. Market Value Forecast, by End-user, 2020-2034
12.4.1. Biopharmaceutical Companies
12.4.2. Nutraceutical Companies
12.4.3. Herbal-based Industries
12.4.4. Others (Research Institutes, etc.)
12.5. Market Value Forecast, by Country/Sub-region, 2020-2034
12.5.1. Brazil
12.5.2. Mexico
12.5.3. Rest of Latin America
12.6. Market Attractiveness Analysis
12.6.1. By Molecule Type
12.6.2. By End-user
12.6.3. By Country/Sub-region
13. Middle East & Africa Natural APIs Market Analysis and Forecast
13.1. Introduction
13.2. Key Findings
13.3. Market Value Forecast, by Molecule Type, 2020-2034
13.3.1. Alkaloids
13.3.2. Phenolic Acids
13.3.3. Terpenoids
13.3.4. Lignin & Stilbenes
13.3.5. Anthocyanin
13.3.6. Flavonoids
13.3.7. Others
13.4. Market Value Forecast, by End-user, 2020-2034
13.4.1. Biopharmaceutical Companies
13.4.2. Nutraceutical Companies
13.4.3. Herbal-based Industries
13.4.4. Others (Research Institutes, etc.)
13.5. Market Value Forecast, by Country/Sub-region, 2020-2034
13.5.1. GCC Countries
13.5.2. South Africa
13.5.3. Rest of Middle East & Africa
13.6. Market Attractiveness Analysis
13.6.1. By Molecule Type
13.6.2. By End-user
13.6.3. By Country/Sub-region
14. Competition Landscape
14.1. Market Player - Competitive Matrix (by Tier and Size of Companies)
14.2. Market Share Analysis, by Company (2023)
14.3. Company Profiles
14.3.1. Roquette Frères SA
14.3.1.1. Company Overview
14.3.1.2. Product Portfolio
14.3.1.3. SWOT Analysis
14.3.1.4. Financial Overview
14.3.1.5. Strategic Overview
14.3.2. Evonik Industries AG
14.3.2.1. Company Overview
14.3.2.2. Product Portfolio
14.3.2.3. SWOT Analysis
14.3.2.4. Financial Overview
14.3.2.5. Strategic Overview
14.3.3. Cargill, Inc.
14.3.3.1. Company Overview
14.3.3.2. Product Portfolio
14.3.3.3. SWOT Analysis
14.3.3.4. Financial Overview
14.3.3.5. Strategic Overview
14.3.4. Novartis AG
14.3.4.1. Company Overview
14.3.4.2. Product Portfolio
14.3.4.3. SWOT Analysis
14.3.4.4. Financial Overview
14.3.4.5. Strategic Overview
14.3.5. Sanofi S.A.
14.3.5.1. Company Overview
14.3.5.2. Product Portfolio
14.3.5.3. SWOT Analysis
14.3.5.4. Financial Overview
14.3.5.5. Strategic Overview
14.3.6. Kothari Phytochemicals & Industries Ltd.
14.3.6.1. Company Overview
14.3.6.2. Product Portfolio
14.3.6.3. SWOT Analysis
14.3.6.4. Financial Overview
14.3.6.5. Strategic Overview
14.3.7. Centroflora Group
14.3.7.1. Company Overview
14.3.7.2. Product Portfolio
14.3.7.3. SWOT Analysis
14.3.7.4. Financial Overview
14.3.7.5. Strategic Overview
14.3.8. Arboris, LLC
14.3.8.1. Company Overview
14.3.8.2. Product Portfolio
14.3.8.3. SWOT Analysis
14.3.8.4. Financial Overview
14.3.8.5. Strategic Overview
14.3.9. BASF SE
14.3.9.1. Company Overview
14.3.9.2. Product Portfolio
14.3.9.3. SWOT Analysis
14.3.9.4. Financial Overview
14.3.9.5. Strategic Overview
14.3.10. GSK plc
14.3.10.1. Company Overview
14.3.10.2. Product Portfolio
14.3.10.3. SWOT Analysis
14.3.10.4. Financial Overview
14.3.10.5. Strategic Overview
List of Tables
Table 01: Global Natural APIs Market Size (US$ Bn) Forecast, by Molecule Type, 2020-2034
Table 02: Global Natural APIs Market Size (US$ Bn) Forecast, by End-user, 2020-2034
Table 03: Global Natural APIs Market Size (US$ Bn) Forecast, by Region, 2020-2034
Table 04: North America Natural APIs Market Size (US$ Bn) Forecast, by Country, 2020-2034
Table 05: North America Natural APIs Market Size (US$ Bn) Forecast, by Molecule Type, 2020-2034
Table 06: North America Natural APIs Market Size (US$ Bn) Forecast, by End-user, 2020-2034
Table 07: Europe Natural APIs Market Size (US$ Bn) Forecast, by Country/Sub-region, 2020-2034
Table 08: Europe Natural APIs Market Size (US$ Bn) Forecast, by Molecule Type, 2020-2034
Table 09: Europe Natural APIs Market Size (US$ Bn) Forecast, by End-user, 2020-2034
Table 10: Asia Pacific Natural APIs Market Size (US$ Bn) Forecast, by Country/Sub-region, 2020-2034
Table 11: Asia Pacific Natural APIs Market Size (US$ Bn) Forecast, by Molecule Type, 2020-2034
Table 12: Asia Pacific Natural APIs Market Size (US$ Bn) Forecast, by End-user, 2020-2034
Table 13: Latin America Natural APIs Market Size (US$ Bn) Forecast, by Country/Sub-region, 2020-2034
Table 14: Latin America Natural APIs Market Size (US$ Bn) Forecast, by Molecule Type, 2020-2034
Table 15: Latin America Natural APIs Market Size (US$ Bn) Forecast, by End-user, 2020-2034
Table 16: Middle East & Africa Natural APIs Market Size (US$ Bn) Forecast, by Country/Sub-region, 2020-2034
Table 17: Middle East & Africa Natural APIs Market Size (US$ Bn) Forecast, by Molecule Type, 2020-2034
Table 18: Middle East & Africa Natural APIs Market Size (US$ Bn) Forecast, by End-user, 2020-2034
List of Figures
Figure 01: Global Natural APIs Market Size (US$ Bn) and Distribution (%), by Region, 2023 and 2034
Figure 02: Global Natural APIs Market Revenue (US$ Bn), by Molecule Type, 2023
Figure 03: Global Natural APIs Market Value Share, by Molecule Type, 2023
Figure 04: Global Natural APIs Market Revenue (US$ Bn), by End-user, 2023
Figure 05: Global Natural APIs Market Value Share, by End-user, 2023
Figure 06: Global Natural APIs Market Value Share, by Region, 2023
Figure 07: Global Natural APIs Market Value (US$ Bn) Forecast, 2020-2034
Figure 08: Global Natural APIs Market Value Share Analysis, by Molecule Type, 2023 and 2034
Figure 09: Global Natural APIs Market Attractiveness Analysis, by Molecule Type, 2020-2034
Figure 10: Global Natural APIs Market Value Share Analysis, by End-user, 2023 and 2034
Figure 11: Global Natural APIs Market Attractiveness Analysis, by End-user, 2020-2034
Figure 12: Global Natural APIs Market Value Share Analysis, by Region, 2023 and 2034
Figure 13: Global Natural APIs Market Attractiveness Analysis, by Region, 2020-2034
Figure 14: North America Natural APIs Market Value (US$ Bn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 15: North America Natural APIs Market Attractiveness Analysis, by Country, 2020-2034
Figure 16: North America Natural APIs Market Value Share Analysis, by Country, 2023 and 2034
Figure 17: North America Natural APIs Market Value Share Analysis, by Molecule Type, 2023 and 2034
Figure 18: North America Natural APIs Market Value Share Analysis, by End-user, 2023 and 2034
Figure 19: North America Natural APIs Market Attractiveness Analysis, by Molecule Type, 2020-2034
Figure 20: North America Natural APIs Market Attractiveness Analysis, by End-user, 2020-2034
Figure 21: Europe Natural APIs Market Value (US$ Bn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 22: Europe Natural APIs Market Attractiveness Analysis, by Country/Sub-region, 2020-2034
Figure 23: Europe Natural APIs Market Value Share Analysis, by Country/Sub-region, 2023 and 2034
Figure 24: Europe Natural APIs Market Value Share Analysis, by Molecule Type, 2023 and 2034
Figure 25: Europe Natural APIs Market Value Share Analysis, by End-user, 2023 and 2034
Figure 26: Europe Natural APIs Market Attractiveness Analysis, by Molecule Type, 2020-2034
Figure 27: Europe Natural APIs Market Attractiveness Analysis, by End-user, 2020-2034
Figure 28: Asia Pacific Natural APIs Market Value (US$ Bn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 29: Asia Pacific Natural APIs Market Attractiveness Analysis, by Country/Sub-region, 2020-2034
Figure 30: Asia Pacific Natural APIs Market Value Share Analysis, by Country/Sub-region, 2023 and 2034
Figure 31: Asia Pacific Natural APIs Market Value Share Analysis, by Molecule Type, 2023 and 2034
Figure 32: Asia Pacific Natural APIs Market Value Share Analysis, by End-user, 2023 and 2034
Figure 33: Asia Pacific Natural APIs Market Attractiveness Analysis, by Molecule Type, 2020-2034
Figure 34: Asia Pacific Natural APIs Market Attractiveness Analysis, by End-user, 2020-2034
Figure 35: Latin America Natural APIs Market Value (US$ Bn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 36: Latin America Natural APIs Market Attractiveness Analysis, by Country/Sub-region, 2020-2034
Figure 37: Latin America Natural APIs Market Value Share Analysis, by Country/Sub-region, 2023 and 2034
Figure 38: Latin America Natural APIs Market Value Share Analysis, by Molecule Type, 2023 and 2034
Figure 39: Latin America Natural APIs Market Value Share Analysis, by End-user, 2023 and 2034
Figure 40: Latin America Natural APIs Market Attractiveness Analysis, by Molecule Type, 2020-2034
Figure 41: Latin America Natural APIs Market Attractiveness Analysis, by End-user, 2020-2034
Figure 42: Middle East & Africa Natural APIs Market Size (US$ Bn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 43: Middle East & Africa Natural APIs Market Attractiveness Analysis, by Country/Sub-region, 2020-2034
Figure 44: Middle East & Africa Natural APIs Market Value Share Analysis, by Country/Sub-region, 2023 and 2034
Figure 45: Middle East & Africa Natural APIs Market Value Share Analysis, by Molecule Type, 2023 and 2034
Figure 46: Middle East & Africa Natural APIs Market Value Share Analysis, by End-user, 2023 and 2034
Figure 47: Middle East & Africa Natural APIs Market Attractiveness Analysis, by Molecule Type, 2020-2034
Figure 48: Middle East & Africa Natural APIs Market Attractiveness Analysis, by End-user, 2020-2034