Rise in incidence of bone and tissue injury is the factor basically responsible for the insulin-like growth factors (IGFs) market growth. Insulin-like growth factors majorly participate in the growth and functioning of every organ in the body, and are partly responsible for reduction in blood glucose levels. Need for cellular proliferation is another factor promoting the expansion of IGF proteins industry.
The insulin-like growth factors (IGFs) market manufacturers are working toward adoption of the outcome that insulin-like growth factor 2 receptor is one of the key immune-related genes correlated to poor prognosis in the patients suffering from triple-negative breast cancer.
Insulin-like growth factors (IGFs) industry are referred to as proteins that have high sequence similarity to insulin. They are part of a complex system used by cells for communicating with physiologic environment.
This complex system, also called IGF axis, comprises two cell-surface receptors (IGF1R and IGF2R), two ligands (IGF-1 and IGF-2), a family of seven high-affinity IGF-binding proteins (IGFBP1 to IGFBP7), along with associated IGFBP degrading enzymes , which are collectively called proteases.
IGFs are known for decreasing the chance to develop cancer, diabetes, and malnutrition. Their regulatory systems in diverse organs are tissue-specific, which include heart, kidney, liver, and various other tissues, but all of them share similar components.
Advantages of IGF01 peptides include boosting the metabolic rate, enhancing libido and energy levels, helping to elevate feeling of depression, bolstering cognitive function, and increasing muscle binding capacities.
However, research states that IGFs are bound to induce side-effects such as retinal edema, impaired glucose metabolism and hypoglycemia, fatigue, muscle pain, and alterations in sexual function. These side-effects may restrain the insulin-like growth factors market going forward.
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Insulin-like Growth Factors (IGFs) Market Drivers |
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The liver is known for secreting IGF-1, which is the basic IGF found in bone cells, cartilage, and muscles. IGF-1 basically binds to IGF-1 receptor (IGF1R), i.e. tyrosine kinase receptor. This binding triggers intracellular signaling and catalyzes cell differentiation and proliferation. They also help in tissue repair.
Research states that IGF-1’s higher concentrations in fetuses result in bigger fetal size. From animal studies, it has been inferred that deficiency of IGF-1 is linked with impaired neurological development, which suggests that the hormone has exclusive roles in myelination and axonal growth. The deficiency of this IGF is also linked with neonatal mortality.
As IGFs are promoters of growth, the studies have shown that IGF’1’s blood levels progressively increase during childhood and are at peak during puberty.
Rise in cellular proliferation as mentioned above is thus expanding the insulin-like growth factors (IGFs) market size.
IGF-1, during the first phase of bone repair, stimulates proliferation of osteoblast and promotes the formation of bone matrix through 100% differentiated osteoblasts. IGF-II acts at the subsequent stage of endochondral bone formation and triggers type I collagen production, cell proliferation, and cartilage matrix synthesis.
As per the WHO, 440 million people suffer from osteoarthritis globally, followed by neck pain (222 million people), amputations (180 million people), and others. Moreover, increase in the number of sports enthusiasts is resulting in rise in the number of bone fractures worldwide.
Need to effectively check bone and tissue injuries is thus accelerating the insulin-like growth factors (IGFs) market demand.
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Leading Region | North America |
As per the latest insulin-like growth factors market analysis, North America led the growth factors (IGFs) landscape in 2023 and the status quo is expected to remain unchanged during the forecast period. This is attributed to increase in the number of patients contracting bone and tissue injuries in the U.S. and Canada.
Asia Pacific’s significant insulin-like growth factors (IGFs) market share is due to rise in the number of sports activities in countries such as India. Moreover, rise in awareness regarding the importance of timely treatment of these injuries is keeping the momentum for the market.
Boehringer Ingelheim International GmbH, Genervon Biopharmaceuticals LLC, Ascendis Pharma, Regulaxis SAS, and MedImmune, LLC are some of the key players covered in the insulin-like growth factors (IGFs) market report.
These companies have been profiled based on parameters such as company overview, business strategies, financial overview, product portfolio, and business segments.
Attribute | Detail |
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Market Size in 2023 | US$ 274.4 Mn |
Market Forecast (Value) in 2034 | US$ 511.4 Mn |
Growth Rate (CAGR) | 5.87% |
Forecast Period | 2024-2034 |
Historical Data Available for | 2020-2022 |
Quantitative Units | US$ Bn for Value |
Market Analysis | It includes segment analysis as well as regional level analysis. Moreover, qualitative analysis includes drivers, restraints, opportunities, key trends, Porter’s Five Forces analysis, value chain analysis, and key trend analysis. |
Competition Landscape |
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Format | Electronic (PDF) + Excel |
Market Segmentation |
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Regions Covered |
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Countries Covered |
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Companies Profiled |
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Customization Scope | Available Upon Request |
Pricing | Available Upon Request |
It was valued at US$ 274.4 Mn in 2023
It is projected to grow at a CAGR of 5.8% from 2024 to 2034
Preference for cellular proliferation and growing prevalence of bone and tissue injury
Hospital pharmacies segment accounted for the largest share in 2023
North America was the dominant region in 2023
Boehringer Ingelheim International GmbH, Genervon Biopharmaceuticals LLC, Ascendis Pharma, Regulaxis SAS, and MedImmune, LLC
1. Preface
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary: Global Insulin-like Growth Factors (IGFs) Market
4. Market Overview
4.1. Introduction
4.1.1. Product Definition
4.1.2. Industry Evolution/Developments
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Insulin-like Growth Factors (IGFs) Market Analysis and Forecast, 2020-2034
5. Key Insights
5.1. Pipeline Analysis
5.2. Key Product/Brand Analysis
5.3. Key Mergers & Acquisitions
5.4. COVID-19 Pandemic Impact on Industry
6. Global Insulin-like Growth Factors (IGFs) Market Analysis and Forecast, by Type
6.1. Introduction & Definition
6.2. Key Findings/Developments
6.3. Market Value Forecast, by Type, 2020-2034
6.3.1. Mechano Growth Factor
6.3.2. Somatomedin C
6.3.3. IGF 1
6.4. Market Attractiveness Analysis, by Type
7. Global Insulin-like Growth Factors (IGFs) Market Analysis and Forecast, by End-user
7.1. Introduction & Definition
7.2. Key Findings/Developments
7.3. Market Value Forecast, by End-user, 2020-2034
7.3.1. Hospitals
7.3.2. Medical Centers
7.4. Market Attractiveness Analysis, by End-user
8. Global Insulin-like Growth Factors (IGFs) Market Analysis and Forecast, by Region
8.1. Key Findings
8.2. Market Value Forecast, by Region, 2020-2034
8.2.1. North America
8.2.2. Europe
8.2.3. Asia Pacific
8.2.4. Latin America
8.2.5. Middle East & Africa
8.3. Market Attractiveness Analysis, by Region
9. North America Insulin-like Growth Factors (IGFs) Market Analysis and Forecast
9.1. Introduction
9.2. Key Findings
9.3. Market Value Forecast, by Type, 2020-2034
9.3.1. Mechano Growth Factor
9.3.2. Somatomedin C
9.3.3. IGF 1
9.4. Market Value Forecast, by End-user, 2020-2034
9.4.1. Hospitals
9.4.2. Medical Centers
9.5. Market Value Forecast, by Country, 2020-2034
9.5.1. U.S.
9.5.2. Canada
9.6. Market Attractiveness Analysis
9.6.1. By Type
9.6.2. By End-user
9.6.3. By Country
10. Europe Insulin-like Growth Factors (IGFs) Market Analysis and Forecast
10.1. Introduction
10.2. Key Findings
10.3. Market Value Forecast, by Type, 2020-2034
10.3.1. Mechano Growth Factor
10.3.2. Somatomedin C
10.3.3. IGF 1
10.4. Market Value Forecast, by End-user, 2020-2034
10.4.1. Hospitals
10.4.2. Medical Centers
10.5. Market Value Forecast, by Country/Sub-region, 2020-2034
10.5.1. Germany
10.5.2. U.K.
10.5.3. France
10.5.4. Italy
10.5.5. Spain
10.5.6. Rest of Europe
10.6. Market Attractiveness Analysis
10.6.1. By Type
10.6.2. By End-user
10.6.3. By Country/Sub-region
11. Asia Pacific Insulin-like Growth Factors (IGFs) Market Analysis and Forecast
11.1. Introduction
11.2. Key Findings
11.3. Market Value Forecast, by Type, 2020-2034
11.3.1. Mechano Growth Factor
11.3.2. Somatomedin C
11.3.3. IGF 1
11.4. Market Value Forecast, by End-user, 2020-2034
11.4.1. Hospitals
11.4.2. Medical Centers
11.5. Market Value Forecast, by Country/Sub-region, 2020-2034
11.5.1. China
11.5.2. Japan
11.5.3. India
11.5.4. Australia & New Zealand
11.5.5. Rest of Asia Pacific
11.6. Market Attractiveness Analysis
11.6.1. By Type
11.6.2. By End-user
11.6.3. By Country/Sub-region
12. Latin America Insulin-like Growth Factors (IGFs) Market Analysis and Forecast
12.1. Introduction
12.2. Key Findings
12.2.1. Mechano Growth Factor
12.2.2. Somatomedin C
12.2.3. IGF 1
12.3. Market Value Forecast, by End-user, 2020-2034
12.3.1. Hospitals
12.3.2. Medical Centers
12.4. Market Value Forecast, by Country/Sub-region, 2020-2034
12.4.1. Brazil
12.4.2. Mexico
12.4.3. Rest of Latin America
12.5. Market Attractiveness Analysis
12.5.1. By Type
12.5.2. By End-user
12.5.3. By Country/Sub-region
13. Middle East & Africa Insulin-like Growth Factors (IGFs) Market Analysis and Forecast
13.1. Introduction
13.2. Key Findings
13.3. Market Value Forecast, by Type, 2020-2034
13.3.1. Mechano Growth Factor
13.3.2. Somatomedin C
13.3.3. IGF 1
13.4. Market Value Forecast, by End-user, 2020-2034
13.4.1. Hospitals
13.4.2. Medical Centers
13.5. Market Value Forecast, by Country/Sub-region, 2020-2034
13.5.1. GCC Countries
13.5.2. South Africa
13.5.3. Rest of Middle East & Africa
13.6. Market Attractiveness Analysis
13.6.1. By Type
13.6.2. By End-user
13.6.3. By Country/Sub-region
14. Competition Landscape
14.1. Market Player - Competitive Matrix (by Tier and Size of Companies)
14.2. Market Share Analysis, by Company (2023)
14.3. Company Profiles
14.3.1. Boehringer Ingelheim International GmbH
14.3.1.1. Company Overview
14.3.1.2. Product Portfolio
14.3.1.3. SWOT Analysis
14.3.1.4. Financial Overview
14.3.1.5. Strategic Overview
14.3.2. Genervon Biopharmaceuticals LLC
14.3.2.1. Company Overview
14.3.2.2. Product Portfolio
14.3.2.3. SWOT Analysis
14.3.2.4. Financial Overview
14.3.2.5. Strategic Overview
14.3.3. Ascendis Pharma
14.3.3.1. Company Overview
14.3.3.2. Product Portfolio
14.3.3.3. SWOT Analysis
14.3.3.4. Financial Overview
14.3.3.5. Strategic Overview
14.3.4. Regulaxis SAS
14.3.4.1. Company Overview
14.3.4.2. Product Portfolio
14.3.4.3. SWOT Analysis
14.3.4.4. Financial Overview
14.3.4.5. Strategic Overview
14.3.5. MedImmune, LLC
14.3.5.1. Company Overview
14.3.5.2. Product Portfolio
14.3.5.3. SWOT Analysis
14.3.5.4. Financial Overview
14.3.5.5. Strategic Overview
List of Tables
Table 01: Global Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Type, 2020-2034
Table 02: Global Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by End-user, 2020-2034
Table 03: Global Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Region, 2020-2034
Table 04: North America Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Country, 2020-2034
Table 05: North America Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Type, 2020-2034
Table 06: North America Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by End-user, 2020-2034
Table 07: Europe Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Country/Sub-region, 2020-2034
Table 08: Europe Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Type, 2020-2034
Table 09: Europe Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by End-user, 2020-2034
Table 10: Asia Pacific Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Country/Sub-region, 2020-2034
Table 11: Asia Pacific Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Type, 2020-2034
Table 12: Asia Pacific Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by End-user, 2020-2034
Table 13: Latin America Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Country/Sub-region, 2020-2034
Table 14: Latin America Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Type, 2020-2034
Table 15: Latin America Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by End-user, 2020-2034
Table 16: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Country/Sub-region, 2020-2034
Table 17: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by Type, 2020-2034
Table 18: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast, by End-user, 2020-2034
List of Figures
Figure 01: Global Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) and Distribution (%), by Region, 2023 and 2034
Figure 02: Global Insulin-like Growth Factors (IGFs) Market Revenue (US$ Mn), by Type, 2023
Figure 03: Global Insulin-like Growth Factors (IGFs) Market Value Share, by Type, 2023
Figure 04: Global Insulin-like Growth Factors (IGFs) Market Revenue (US$ Mn), by End-user, 2023
Figure 05: Global Insulin-like Growth Factors (IGFs) Market Value Share, by End-user, 2023
Figure 06: Global Insulin-like Growth Factors (IGFs) Market Value Share, by Region, 2023
Figure 07: Global Insulin-like Growth Factors (IGFs) Market Value (US$ Mn) Forecast, 2020-2034
Figure 08: Global Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Type, 2023 and 2034
Figure 09: Global Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Type, 2020-2034
Figure 10: Global Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by End-user, 2023 and 2034
Figure 11: Global Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by End-user, 2020-2034
Figure 12: Global Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Region, 2023 and 2034
Figure 13: Global Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Region, 2020-2034
Figure 14: North America Insulin-like Growth Factors (IGFs) Market Value (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 15: North America Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Country, 2020-2034
Figure 16: North America Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Country, 2023 and 2034
Figure 17: North America Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Type, 2023 and 2034
Figure 18: North America Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by End-user, 2023 and 2034
Figure 19: North America Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Type, 2020-2034
Figure 20: North America Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by End-user, 2020-2034
Figure 21: Europe Insulin-like Growth Factors (IGFs) Market Value (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 22: Europe Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Country/Sub-region, 2020-2034
Figure 23: Europe Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Country/Sub-region, 2023 and 2034
Figure 24: Europe Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Type, 2023 and 2034
Figure 25: Europe Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by End-user, 2023 and 2034
Figure 26: Europe Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Type, 2020-2034
Figure 27: Europe Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by End-user, 2020-2034
Figure 28: Asia Pacific Insulin-like Growth Factors (IGFs) Market Value (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 29: Asia Pacific Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Country/Sub-region, 2020-2034
Figure 30: Asia Pacific Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Country/Sub-region, 2023 and 2034
Figure 31: Asia Pacific Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Type, 2023 and 2034
Figure 32: Asia Pacific Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by End-user, 2023 and 2034
Figure 33: Asia Pacific Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Type, 2020-2034
Figure 34: Asia Pacific Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by End-user, 2020-2034
Figure 35: Latin America Insulin-like Growth Factors (IGFs) Market Value (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 36: Latin America Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Country/Sub-region, 2020-2034
Figure 37: Latin America Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Country/Sub-region, 2023 and 2034
Figure 38: Latin America Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Type, 2023 and 2034
Figure 39: Latin America Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by End-user, 2023 and 2034
Figure 40: Latin America Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Type, 2020-2034
Figure 41: Latin America Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by End-user, 2020-2034
Figure 42: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Size (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034
Figure 43: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Country/Sub-region, 2020-2034
Figure 44: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Country/Sub-region, 2023 and 2034
Figure 45: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by Type, 2023 and 2034
Figure 46: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Value Share Analysis, by End-user, 2023 and 2034
Figure 47: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by Type, 2020-2034
Figure 48: Middle East & Africa Insulin-like Growth Factors (IGFs) Market Attractiveness Analysis, by End-user, 2020-2034